NOF CORPORATION

Activated PEGs for PEGylation

Welcome to our Website on Activated PEGs for PEGylation

NOF supplies various kinds of high-pure activated polyethylene glycoliPEGjderivatives -
SUNBRIGHT® series.
Having over 20 years of experience in supplying high-quality methoxy polyethylene glycol, starting material of PEG derivatives, which are patented through our proprietary technology, NOF SUNBRIGHT® series have great features such as narrow polydispersity and extremely low impurity profile.
Representing Monofunctional Linear type, Branched type, Multi-Arm / Bi-Functional type and Heterofunctional type structures can be conjugated with terminal ends, like Maleimide, Aldehyde, Oxy-amine etc. and their molecular weights range from 2kDa to 80kDa. Extensive product line-up enables pharmacokinetics scientists to specifically modify their APIs.

NOF SUNBRIGHT® series are suitable for a wide variety application of drug delivery technologies, such as PEGylated protein drug, PEGylated nano-particles like liposome and polymer micelles, PEG Hydrogels, and PEG linker for antibody conjugated nano-particle.



NOF is capable of manufacturing these activated PEGs from small reagent scale to large commercial quantities in a state-of-the-art cGMP facility, which was built in 2005, designed only for manufacturing PEG derivatives.
From business offices in Tokyo, New York and Belgium, NOF promotes high quality products to pharmaceutical companies thorough out the world.


Improving Drug Potency and Efficacy by Nanocarrier-Mediated Subcellular Targeting
Sci Transl Med 5 January 2011: Vol. 3, Issue 64, p. 64ra2
AbstractF http://stm.sciencemag.org/content/3/64/64ra2.abstract
Polymeric Micelle Carrier


PEGylated Phospholipid